Coeliac sprue-associated membranoproliferative glomerulonephritis (MPGN)

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Coeliac sprue-associated membranoproliferative glomerulonephritis (MPGN).

Coeliac sprue (CS) may occur in association with immune complex-mediated diseases, including IgA nephropathy, dermatitis herpetiformis and thyroiditis. An association of CS with membranoproliferative glomerulonephritis (MPGN) type 1 is rare, with only two prior cases reported. Here we describe a 45-year-old man with no prior medical history who presented initially with microhaematuria, subnephr...

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Successful treatment of hepatitis B virus (HBV)-associated membranoproliferative glomerulonephritis (MPGN) with alpha interferon.

but he had received a number of vaccinations using reusable needles during the 1960s and 1970s. There Introduction was no past history of kidney disease, hypertension or diabetes mellitus. Adult-onset membranoproliferative glomerulonephritis (MPGN) has a poor prognosis with 50% Investigations mortality or development of end-stage renal failure His 24-h urinary protein was 10.6 g/day, albumin (E...

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Familial MPGN - a case series: a clinical description of familial membranoproliferative glomerulonephritis amongst three Irish families.

Genetic factors have been implicated in the pathogenesis of certain cases of MPGN. Familial cases of all three histological subtypes have been described. Genetic defects in the control of complement pathways appear to be at the root of many hereditary forms of MPGN. Here we describe a series of three families with familial MPGN. We have identified 3 individuals with a diagnosis of idiopathic MP...

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Pathological aspects of membranoproliferative glomerulonephritis (MPGN) and haemolytic uraemic syndrome (HUS) / thrombocytic thrombopenic purpura (TTP).

In this paper, epidemiology, pathogenesis and typical morphological aspects of all three types of membranoproliferative glomerulonephritis (MPGN), of the haemolytic uraemic syndrome (HUS) as well as of thrombotic thrombopenic purpura (TTP) will be reviewed on the light microscopical, immunohistological or immunofluorescence and electron microscopical level. In particular, differences in the pat...

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Membranoproliferative Glomerulonephritis

Membranoproliferative glomerulonephritis (MPGN) refers to glomerular pathology in which there is thickening of the capillary wall together with mesangial expansion. In this article we firstly review the pathological features of MPGN and discuss how advances in our understanding of the association between abnormalities in the regulation of complement and MPGN have revealed limitations in the his...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2009

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfp353